Recombinant Human BMP-4
货号：120-05-1,120-05-100,120-05-1000,120-05-5,120-05-50,120-05-500
规格：1ug,100ug,1mg,5ug,50ug,500ug
价格：640,14297,65632,1560,8429,42582
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：120-05产品描述：Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant Human BMP-4, expressed in HeLa cells, is a 25.6 kDa homodimeric glycoprotein.Source:HeLa cellsSynonyms:Bone Morphogenetic Protein-4, BMP-2B, DVR4AA Sequence (monomer):HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCRPurity:≥ 97% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expectedED50for this effect is 2-8 ng/ml.Calculated Molecular Weight:25.6 kDaAccession Number:P12644Gene ID:652Note:100μg is the largest vial size for this product.Larger sizes supplied as multiple 50μg and/or 100μg vials.crossreactivity:Human,Mouse,Mouse + Rat,Pig,RatCountry Of Origin:USANot for human use. |
| product.subtitle.recentcitations |
| 第一作者 | Zhang, M |
| 标题 | The transcription factor TFCP2L1 promotes primordial germ cell-like cell specification of pluripotent stem cells.A non-invasive method to generate induced pluripotent stem cells from primate urine |
| 文献引用 | The Journal of Biological Chemistry; pg101217PubMed Id |
| PubMed Id | 34555410 |
| 第一作者 | Bayerl, J |
| 标题 | Principles of signaling pathway modulation for enhancing human naive pluripotency induction. |
| 文献引用 | Cell Stem Cell; 28(9) pg1549-1565.e12PubMed Id |
| PubMed Id | 33915080 |
| 第一作者 | Monteiro, D A |
| 标题 | Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes. |
| 文献引用 | FASEB journal : official publication of the Federation of American Societies for Experimental Biology; 35(3) pge21263PubMed Id |
| PubMed Id | 33570811 |
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