Recombinant Human CTGFL/WISP-2
货号：120-16-5,120-16-500,120-16-250,120-16-100,120-16-20,120-16-1000
规格：5ug,500ug,250ug,100ug,20ug,1mg
价格：582,21570,14522,8297,1418,33241
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：120-16产品描述：CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine-rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, the ovaries, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant Human CTGFL/WISP-2 is a 24.3 kDa protein consisting of 228 amino acid residues.Mature human CTGFL/WISP-2 is a 24.8 kDa polypeptide protein containing 227 amino acids. It is composed of 3 distinct domains; the IGF-Binding Protein domain (IGF-BP), the Thrombospondin type I repeat (TSP type I), and von Willebrand Factor C motif (VWFC).Source:E.coliSynonyms:Connective Tissue Growth Factor-Like protein, CCN5, CT-58AA Sequence:MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAFPurity:≥ 95% by SDS-PAGE gel and HPLC analyses.Biological Activity:TheED50was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/ml in the presence of 15 ng/ml of human IGF-II.Calculated Molecular Weight:24.3 kDaAccession Number:O76076Gene ID:8839crossreactivity:Human,MouseCountry Of Origin:USANot for human use. |
QQ:1749072012