Recombinant Human FGF-18
货号：100-28-100,100-28-1000,100-28-25,100-28-250,100-28-5,100-28-500
规格：100ug,1mg,25ug,250ug,5ug,500ug
价格：7016,28131,1560,12277,640,18247
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：FGF-18 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-18 derived fromE.coliis a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full length protein.来源:E.coli别名:Fibroblast Growth Factor-18, zFGF5, FGFI氨基酸序列:AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by a cell proliferation assay using Balb/c 3T3 cells. The expectedED50is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105units/mg.Calculated Molecular Weight:20.1 kDaAccession Number:O76093Gene ID:8817交叉反应:Human,Mouse,Rat,Sheep |
product.subtitle.recentcitations |
第一作者 | Zhang, J |
标题 | FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential |
文献引用 | Oncogene; |
PubMed Id | 32934314 |
第一作者 | Cinque, L |
标题 | MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. |
文献引用 | The EMBO Journal; pge105696 |
PubMed Id | 32716134 |
第一作者 | Savchenko, E |
标题 | FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. |
文献引用 | Scientific Reports; 9(1) pg9610 |
PubMed Id | 31270389 |
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