Recombinant Human FGF-23
货号：100-52-100,100-52-1000,100-52-20,100-52-250,100-52-5,100-52-500
规格：100ug,1mg,20ug,250ug,5ug,500ug
价格：9171,36743,1568,16052,643,23843
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：The FGF family plays a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of aKlothoprotein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant Human FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.来源:E.coli别名:Fibroblast Growth Factor-23氨基酸序列:MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expectedED50for this effect is 2.0-5.0 μg/ml, in the presence of murine Klotho and heparin.Calculated Molecular Weight:25.5 kDaAccession Number:Q9GZV9Gene ID:8074交叉反应：Mouse,Rat原产国:USA |
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