Animal-Free Recombinant Human IGF-BP7

货号：AF-350-09-100,AF-350-09-1000,AF-350-09-25,AF-350-09-250,AF-350-09-5,AF-350-09-500

规格：100ug,1mg,25ug,250ug,5ug,500ug

价格：12700,50820,2830,22230,1250,33030

产品类型：细胞因子添加物

品牌：PeproTech

产品描述：IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.Manufactured using all Animal-Free reagents.来源:E.coli别名:Insulin-like Growth Factor-Binding Protein 7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBP-rP1)氨基酸序列:SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Not available.Calculated Molecular Weight:26.4 kDaAccession Number:Q16270Gene ID:3490

技术参数

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