Animal-Free Recombinant Murine LIF
货号：AF-250-02-5,AF-250-02-25,AF-250-02-100,AF-250-02-250,AF-250-02-500,AF-250-02-1000
规格：5µg,25ug,100ug,250ug,500ug,1mg
价格：1250,2830,11930,20880,31030,47740
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：LIF is a pleiotrophic factor produced by multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor. Recombinant Murine LIF is a 19.9 kDa protein containing 180 amino acids residues, including three disulfide bonds.Manufactured using all Animal-Free reagents.来源:E.coli别名:Leukemia Inhibitory Factor, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI), Interleukin 6 family cytokine氨基酸序列:SPLPITPVNA TCAIRHPCHG NLMNQIKNQL AQLNGSANAL FISYYTAQGE PFPNNVEKLC APNMTDFPSF HGNGTEKTKL VELYRMVAYL SASLTNITRD QKVLNPTAVS LQVKLNATID VMRGLLSNVL CRLCNKYRVG HVDVPPVPDH SDKEAFQRKK LGCQLLGTYK QVISVVVQAF纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:PeproTech's Murine LIF is fully biologically active when compared to standards. TheED50as determined by the M1 cell differentiation assay is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.Calculated Molecular Weight:19.6 kDaAccession Number:P09056Gene ID:16878交叉反应:Mouse原产国:USA |
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