Animal-Free Recombinant Human IL-22
货号:AF-200-22-2,AF-200-22-10,AF-200-22-100,AF-200-22-250,AF-200-22-500,AF-200-22-1000
规格:2µg,10µg,100µg,250µg,500µg,1mg
价格:1250,2830,21940,38400,57050,87780
产品类型:细胞因子添加物
品牌:PeproTech
产品详情产品编号:AF-200-22产品描述:IL-22 is a member of the IL-10 family of regulatory cytokines, which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10Rβ/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant Human IL-22 is a 33.6 kDa, non-disulfide-linked, homodimeric protein consisting of two 147 amino acid polypeptide chains.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Interleukin-22, IL-TIF, Cytokine ZCYTO18AA Sequence (monomer):MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACIPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The expectedED50for this effect is 0.7- 1.0 ng/ml.Calculated Molecular Weight:33.6 kDaAccession Number:Q9GZX6Gene ID:50616crossreactivity:HumanCountry Of Origin:USANot for human use. |
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