Human VEGF-D
货号：100-20D-10,100-20D-100,100-20D-1000,100-20D-2,100-20D-250,100-20D-500
规格：10ug,100ug,1mg,2ug,250ug,500ug
价格：1568,12235,48997,643,21395,31787
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surface-associated, non-covalent, disulfide-linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant Human VEGF-D is a 26.2 kDa, non-disulfide linked, homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation, the protein migrates as a 20.0-22.0 kDa band by SDS-PAGE analysis under non-reducing conditions.别名:Vascular Endothelial Growth Factor-D, FIGF氨基酸序列:FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR来源:HEK293 cells纯度:Greater than 95% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to bind immobilized recombinant human Neuropilin-1 in an ELISA.Calculated Molecular Weight:26.2 kDaAccession Number:O43915Gene ID:2277原产国:USA仅用于研究。不适用于诊断或治疗。 |
product.subtitle.recentcitations |
第一作者 | Guo, R |
标题 | Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors. |
文献引用 | Cell Research; 30(1) pg21-33 |
PubMed Id | 31729468 |
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