Recombinant Human sTRAIL Receptor-1

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Recombinant Human sTRAIL Receptor-1

货号:310-18-10,310-18-100,310-18-1000,310-18-250,310-18-50,310-18-500

规格:10ug,100ug,1mg,250ug,50ug,500ug

价格:585,3202,12850,5608,1425,8332

产品类型:细胞因子添加物

品牌:PeproTech

产品描述:TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins, and contain a cytoplasmic "death domain," which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane-anchored or soluble TRAIL/Apo2L. The DR4 and DR5 receptors are both produced as type I transmembrane proteins, which contain an extracellular domain, a transmembrane domain, and a cytoplasmic domain. The recombinant soluble forms of DR4 and DR5 consist of the TNFR-homologous, cysteine-rich portion of their respective extracellular domains. Recombinant Human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine-rich portion of the extracellular domain.来源:E.coli别名:soluble TRAIL Receptor-1, DR4, TNFRSF10A, Apo2氨基酸序列:SGTGAAAATP SKVWGSSAGR IEPRGGGRGA LPTSMGQHGP SARARAGRAP GPRPAREASP RLRVHKTFKF VVVGVLLQVV PSSAATIKLH DQSIGTQQWE HSPLGELCPP GSHRSERPGA CNRCTEGVGY TNASQQLFAC LPCTACKSDE EERSPCTTTR NTACQCKPGT FRNDNSAEMC RKCSTGCPRG MVKVKDCTPW SDIECVHKES GNGHN纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to inhibit apoptosis in LN-18 cells. The expectedED50for this effect is 0.4 -0.5 µg/ml.Calculated Molecular Weight:22.7 kDaAccession Number:O00220Gene ID:8797原产国:USA

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