Recombinant Human IL-36β (IL-1F8)
货号：200-36B-10,200-36B-100,200-36B-1000,200-36B-2,200-36B-250,200-36B-500
规格：10ug,100ug,1mg,2ug,250ug,500ug
价格：1425,11123,44543,585,19450,28897
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-κB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant Human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.别名:Interleukin-36β, IL-1F8, IL-1H2, IL-1 eta氨基酸序列:MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to induce IL-8 production by human PBMCs.Calculated Molecular Weight:17.3 kDaAccession Number:Q9NZH7Gene ID:27177交叉反应:Human原产地:USA仅用于科研，不能用于临床和诊断。 |
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