Recombinant Human MIF
货号：300-69-5,300-69-100,300-69-1000,300-69-25,300-69-250,20200
规格：5µg,100ug,1mg,25ug,250ug,500ug
价格：585,6410,25699,1425,11216,30030
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:Macrophage migration inhibitory factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine, as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-a, IL-1, IL-6, IL-8, and various MMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto-to-enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue. Insect cell-derived Recombinant Human MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.别名:Macrophage Migration, Inhibitory Factor, GLIF, MMIF, GIF, Glycosylation-inhibiting factor氨基酸序列:HHHHHHHHAM PMFIVNTNVP RASVPDGFLS ELTQQLAQAT GKPPQYIAVH VVPDQLMAFG GSSEPCALCS LHSIGKIGGA QNRSYSKLLC GLLAERLRIS PDRVYINYYD MNAANVGWNN STFA来源:Hi-5 Insect cells纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to inhibit monocyte migration.Calculated Molecular Weight:15 kDaAccession Number:P14174Gene ID:4282交叉反应:Mouse, Human原产地:USA仅用于科研，不能用于临床和诊断。 |
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