Anti-Mouse TIGIT PE

admin 2024-10-15 19

Anti-Mouse TIGIT PE

货号:81812-60-25,81812-60-100

规格:25ug,100 μg

价格:1037,2648

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :81812-60

Description

The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells. While in humans it is expressed also on natural killer cells, Treg cells, memory CD4+ and CD8+ T lymphocytes. TIGIT is not expressed on B cells and is upregulated on CD4+ T cells following activation.TIGIT interacts with CD155, and mediates the interaction between natural killer cells or T lymphocytes with APC and fibroblasts and endothelial cells expressing PVR or PVR-like proteins.

Additional Information

Clone

1G9

Format:

PE

Applications

FC

Reactivity

Mouse

Isotype:

Mouse IgG1, kappa

Research Interest:Adaptive Immunity
Cell Type:T Cells,NK and NKT Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Levin, S. D., Taft, D. W., Brandt, C. S., Bucher, C., Howard, E. D., Chadwick, E. M., ... & Lewis, K. E. (2011). Vstm3 is a member of the CD28 family and an important modulator of T-cell function.European journal of immunology,41(4), 902-915.

Joller, N., Hafler, J. P., Brynedal, B., Kassam, N., Spoerl, S., Levin, S. D., ... & Kuchroo, V. K. (2011). Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.The Journal of Immunology,186(3), 1338-1342

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