Anti-Human IFN gamma APC

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Anti-Human IFN gamma APC

货号:80811-80-25,80811-80-100

规格:25 tests,100 μg

价格:1320,3300

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :80811-80

Description

The 4S.B3 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The 4S.B3 antibody neutralizes IFN-γ.

Additional Information

Clone

4S.B3

Format:

APC

Applications

FC, Neutralization,

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Innate Immunity,Adaptive Immunity, Cytokines & Growth Factors
Cell Type:Th1 cells,NK and NKT Cells,T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays.Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.

Meager, A., Parti, S., Barwick, S., Spragg, J., & O'hagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon.Journal of interferon research,4(4), 619-625.

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