Anti-Human IFN gamma PE

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Anti-Human IFN gamma PE

货号:80811-60-25,80811-60-100

规格:25 tests,100 tests

价格:1210,3080

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :80811-60

Description

The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells. The biological activity of IFN-γ is not affected by glycosylation.

Additional Information

Clone

4S.B3

Format:

PE

Applications

FC, Neutralization,

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Innate Immunity,Adaptive Immunity, Cytokines & Growth Factors
Cell Type:Th1 cells,NK and NKT Cells,T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays.Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.

Meager, A., Parti, S., Barwick, S., Spragg, J., & O'hagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon.Journal of interferon research,4(4), 619-625.

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