Anti-Human IFN gamma FITC
货号：80811-50-50,80811-50-25,80811-50-100
规格：50ug,25 tests,100 μg
价格：1430,1210,2420
产品类型：流式抗体
品牌：Biogems
物种：人
宿主：小鼠
抗体亚型：IgG
荧光染料：Purified
Catalogue Number :80811-50
Description
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.
The biological activity of IFN-γ is not affected by glycosylation
Additional Information
Clone | 4S.B3 |
Format: | FITC |
Applications | FC |
Reactivity | Human |
Isotype: | Mouse IgG1, kappa |
| Research Interest: | Innate Immunity,Adaptive Immunity, Cytokines & Growth Factors |
| Cell Type: | Th1 cells,NK and NKT Cells,T Cells |
Preperation: | The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Formulation: | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
References: | Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays.Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105. Prussin, C., & Metcalfe, D. D. (1995). Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.Journal of immunological methods,188(1), 117-128. Jason, J., & Larned, J. (1997). Single-cell cytokine profiles in normal humans: comparison of flow cytometric reagents and stimulation protocols.Journal of immunological methods,207(1), 13-22. |
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