Anti-Human CD278 (ICOS) PE-Cy7

admin 2024-10-16 20

Anti-Human CD278 (ICOS) PE-Cy7

货号:30811-77-25,30811-77-100

规格:25 tests,100 tests

价格:1320,3410

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :30811-77

Description

The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.

Additional Information

Clone

ISA-3

Format:

PE-Cyanine7

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Adaptive Immunity
Cell Type:T Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Hutloff, A., Dittrich, A. M., Beier, K. C., Eljaschewitsch, B., Kraft, R., Anagnostopoulos, I., & Kroczek, R. A. (1999). ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28.Nature,402, 21-24.

Quiroga, M. F., Pasquinelli, V., Martínez, G. J., Jurado, J. O., Zorrilla, L. C., Musella, R. M., ... & García, V. E. (2006). Inducible costimulator: a modulator of IFN-γ production in human tuberculosis.The Journal of Immunology,176(10), 5965-5974.

Buonfiglio, D., Bragardo, M., Redoglia, V., Vaschetto, R., Bottarel, F., Bonissoni, S., ... & Dianzani, U. (2000). The T cell activation molecule H4 and the CD28‐like molecule ICOS are identical.European journal of immunology,30(12), 3463-3467.

技术参数
© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://biorod.cn/thread-15676.htm
产品询价需求提交
最新回复 (0)
返回
发布信息
扫码添加客服微信,咨询产品报价