Anti-Mouse CD117 (c-Kit) APC

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Anti-Mouse CD117 (c-Kit) APC

货号:19112-80-25,19112-80-100

规格:25 μg,100 μg

价格:691,1587

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :19112-80

Description

The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.

Additional Information

Clone

ACK2

Format:

APC

Applications

FC

Reactivity

Mouse

Isotype:

Rat IgG2b, kappa

Research Interest:Angiogenesis
Protein Cross Reactivity:Rat

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., & Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation.The Journal of Immunology,152(10), 4783-4792.

Godfrey, D. I., Zlotnik, A. L. B. E. R. T., & Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development.The Journal of Immunology,149(7), 2281-2285.

Feng, H., Sandlow, J. I., & Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.Molecular reproduction and development,49(3), 317-326.

技术参数
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