Anti-Mouse CD135 (Flt3) PE

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Anti-Mouse CD135 (Flt3) PE

货号:17412-60-50,17412-60-100

规格:50 ug,100 ug

价格:1320,2310

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :17412-60

Description

The A2F10 monoclonal antibody specifically reacts with mouse CD135, a tyrosine kinase class III receptor. CD135, also known as Flt3, Ly-72, and Flk-2, is the receptor for the FLT3 ligand (FLT3L) cytokine and is expressed on many hematopoietic progenitor cells. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. The A2F10 antibody is reported to inhibit the binding of FLT3L to CD135.

Additional Information

Clone

A2F10

Format:

PE

Applications

FC

Reactivity

Mouse

Isotype:

Rat IgG2a, kappa

Research Interest:Stem Cell Research
Cell Type:Stem Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Hannum, C., Culpepper, J., Campbell, D., McClanahan, T., Zurawski, S., Kastelein, R., ... & Lee, F. (1994). Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs.

Ogawa, M., Sugawara, S., Kunisada, T., Sudo, T., Hayashi, S. I., Nishikawa, S., & Kodama, H. (1998). Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse.Experimental hematology,26(6), 478-488.

Matthews, W., Jordan, C. T., Wiegand, G. W., Pardoll, D., & Lemischka, I. R. (1991). A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations.Cell,65(7), 1143-1152.

技术参数
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