Anti-Human CD105 (Endoglin) PE

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Anti-Human CD105 (Endoglin) PE

货号:17111-60-25,17111-60-100

规格:25 tests,100 tests

价格:1210,2640

产品类型:流式抗体

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :17111-60

Description

The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.

Viable U937 cells were stained with PE SN6 in purple with relevant isotype control in blue.

Additional Information

Clone

SN6

Format:

PE

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG1

Research Interest:Stem Cell Research,Angiogenesis
Cell Type:Monocytes and Macrophages,Stem Cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., & Leone, G. (2001). CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia & lymphoma,42(6), 1195-1206.

She, X., Matsuno, F., Harada, N., Tsai, H., & Seon, B. K. (2004). Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐β in suppression of growth of human endothelial cells.International journal of cancer,108(2), 251-257.

Seon, B. K., & Kumar, S. (2002). CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy(pp. 499-515). Humana Press.

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