Anti-Mouse CD103 (Integrin alpha E) SAFIRE Purified

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Anti-Mouse CD103 (Integrin alpha E) SAFIRE Purified

货号:15112-25

规格:100 ug

价格:2428

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :15112-25

Description

The 2E7 monoclonal antibody specifically reacts with mouse CD103, a type I transmembrane glycoprotein in the integrin family that bind to E-cadherin. CD103 is expressed on intraepithelial lymphocyte T cells, peripheral regulatory T cells, lamina propria T cells, and a subset of dendritic cells. It is reported to be involved in T cell homing and immune system regulation.

Additional Information

Clone

2E7

Format:

SAFIRE Purified

Applications

FC, FA

Reactivity

Mouse

Isotype:

Armenian Hamster IgG

Research Interest:Adaptive Immunity
Cell Type:Dendritic Cells,T Cells,Treg cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Hadley, G. A., Bartlett, S. T., Via, C. S., Rostapshova, E. A., & Moainie, S. (1997). The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL.The Journal of Immunology,159(8), 3748-3756.

Schön, M. P., Schön, M., Parker, C. M., & Williams, I. R. (2002). Dendritic Epidermal T Cells (DETC) are Diminished in Integrin &agr; E (CD103)-Deficient Mice.Journal of investigative dermatology,119(1), 190-193.

Zikri, N. N., Schumer, E., Wang, J. J., Gaughan, A., Hadley, G. A., & Moffatt-Bruce, S. D. (2010). Induction of CD4< sup>+</sup> CD25< sup>+</sup> T Regulatory Cells with CD103 Depletion.Journal of Surgical Research,163(1), 162-168.

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