Clone

DX5

Format:

FITC

Applications

FC

Reactivity

Mouse

Isotype:

Rat IgM, kappa

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Arase, H., Saito, T., Phillips, J. H., & Lanier, L. L. (2001). Cutting edge: the mouse NK cell-associated antigen recognized by DX5 moncoclonal antibody is CD49b (α2 integrin, very late antigen-2).The Journal of Immunology,167(3), 1141-1144.

Fernandez, N. C., Lozier, A., Flament, C., Ricciardi-Castagnoli, P., Bellet, D., Suter, M., ... & Zitvogel, L. (1999). Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.Nature medicine,5(4), 405-411.

Gadue, P., & Stein, P. L. (2002). NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation.The Journal of Immunology,169(5), 2397-2406.