Recombinant Human EPO
货号：100-64-100,100-64-1000,100-64-500,100-64-250,100-64-50,100-64-10
规格：100 μg,1000 μg,500 μg,250 μg,50 μg,10 μg
价格：3505,14066,9121,6139,1560,640
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：100-64产品描述：Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EPO in adult mammals are maintained primarily by the kidneys, whereas levels in fetal or neonatal mammals are maintained by the liver. EPO also can exert various non-hematopoietic activities, including vascularization and proliferation of smooth muscle, neural protection during hypoxia, and stimulation of certain B cells. PeproTech’s Human EPO contains 166 amino acid residues and has a calculated molecular weight of approximately 18.4 kDa. As a result of glycosylation, Recombinant Human EPO migrates with an apparent molecular mass of 37.0 kDa by SDS-PAGE gel, under reducing and non-reducing conditions.Source:CHO cellsSynonyms:Erythropoietin, EpoetinAA Sequence:APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDRPurity:≥ 90% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by a cell proliferation assay using TF-1 cells. The expectedED50for this effect is 0.8-1.0 ng/ml.Calculated Molecular Weight:18.4 kDaAccession Number:P01588Gene ID:2056crossreactivity:Human,Human + Virus,MouseCountry Of Origin:USANot for human use. |
| product.subtitle.recentcitations |
| 第一作者 | de Castro Fonseca, M |
| 标题 | Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X. |
| 文献引用 | Iscience; 24(8) pg102841PubMed Id |
| PubMed Id | 34381968 |
| 第一作者 | Bhardwaj, R |
| 标题 | In vitro expansion of fetal liver hematopoietic stem cells. |
| 文献引用 | Scientific Reports; 11(1) pg11879PubMed Id |
| PubMed Id | 34088934 |
| 第一作者 | Ho, T T |
| 标题 | Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions. |
| 文献引用 | The Journal of Experimental Medicine; 218(7) |
| PubMed Id | 34032859 |
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