Human ANGPTL-3

admin 2024-10-15 14

Human ANGPTL-3

货号:130-18-10,130-18-100,130-18-1000,130-18-250,130-18-50,130-18-500

规格:10ug,100ug,1mg,250ug,50ug,500ug

价格:643,3522,14134,6168,1568,9165

产品类型:细胞因子添加物

品牌:PeproTech

产品描述:ANGPTL-3 (Angiopoietin like protein 3) is a member of the angiopoietin family of structurally related proteins, characterized by a coiled N-terminal domain and a C-terminal fibrinogen like domain. It is primarily expressed in the liver and can exert activities related to both angiogenesis and lipid metabolism. ANGPTL-3 inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), which has the effect of increasing plasma levels of triglycerides and HDL associated cholesterol. The fibrinogen like portion of the ANGPTL-3 protein can bind alpha-5/beta-3 integrins leading to endothelial cell adhesion and migration. Recombinant Human ANGPTL-3 is a glycoprotein that migrates by SDS-PAGE analysis at an apparent molecular weight of 62 kDa, and contains 452 amino acid residues including a C-terminal His tag.来源:CHO cells别名:Angiopoietin-like protein 3, ANG-5, ANGPT5氨基酸序列:SRIDQDNSSF DSLSPEPKSR FAMLDDVKIL ANGLLQLGHG LKDFVHKTKG QINDIFQKLN IFDQSFYDLS LQTSEIKEEE KELRRTTYKL QVKNEEVKNM SLELNSKLES LLEEKILLQQ KVKYLEEQLT NLIQNQPETP EHPEVTSLKT FVEKQDNSIK DLLQTVEDQY KQLNQQHSQI KEIENQLRRT SIQEPTEISL SSKPRAPRTT PFLQLNEIRN VKHDGIPAEC TTIYNRGEHT SGMYAIRPSN SQVFHVYCDV ISGSPWTLIQ HRIDGSQNFN ETWENYKYGF GRLDGEFWLG LEKIYSIVKQ SNYVLRIELE DWKDNKHYIE YSFYLGNHET NYTLHLVAIT GNVPNAIPEN KDLVFSTWDH KAKGHFNCPE GYSGGWWWHD ECGENNLNGK YNKPRAKSKP ERRRGLSWKS QNGRLYSIKS TKMLIHPTDS ESFEHHHHHH HH纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its binding ability to recombinant αvβ3 integrin in a functional ELISA.Calculated Molecular Weight:52.9 kDaAccession Number:Q9Y5C1Gene ID:27329交叉反应:Human原产地:USA仅用于科研,不能用于临床和诊断。

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