ANTI-HUMAN CD45 (2D1) PERCP-CY5.5

admin 2024-10-17 18

ANTI-HUMAN CD45 (2D1) PERCP-CY5.5

货号:45-9459-41,45-9459-42

规格:25T,100T

价格:1603,3715

产品类型:流式抗体

品牌:eBioscience

抗原:CD45

物种:人

宿主:小鼠

抗体亚型:IgG

克隆号:2D1

荧光染料:PerCP-Cy5.5

抗体类型:单抗同型对照:Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PerCP-Cyanine5.5
免疫原性:用法:5uL(0.125µg)/test(Flow)
Description: The 2D1 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.Applications Reported: This 2D1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 2D1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.
数据

CD45 Antibody (45-9459-41) in FlowStaining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PerCP-Cyanine5-5 (Product # 45-4714-82) (blue histogram) or Anti-Human CD45 PerCP-Cyanine5-5 (purple histogram). Cells in the lymphocyte gate were used for analysis.
推荐产品:
间充干细胞MSC分选间充干细胞MSC扩增、分化培养基CD73流式抗体细胞因子
参考文献:
1.Scientific reportsAntibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo.2017"45-9459 was used in Flow cytometry/Cell sorting to investigate a novel antibody-dependent cell death pathway."Authors Liew PX,Kim JH,Lee WY,Kubes P2.Cancer researchNeuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.2014"45-9459 was used in Flow cytometry/Cell sorting to demonstrate a mechanism through which HER2-targeting therapies could benefit a larger number of breast cancer patients."Authors Lee CY,Lin Y,Bratman SV,Feng W,Kuo AH,Scheeren FA,Engreitz JM,Varma S,West RB,Diehn M3.Genome biologyQuantitative reconstruction of leukocyte subsets using DNA methylation.2014"45-9459 was used in Flow cytometry/Cell sorting to study how precise immune cell differential estimates can be reconstructed using only DNA rather than whole cells."Authors Accomando WP,Wiencke JK,Houseman EA,Nelson HH,Kelsey KT4.Cancer cellFunctional heterogeneity of genetically defined subclones in acute myeloid leukemia.2014"45-9459 was used in Flow cytometry/Cell sorting to demonstrate the importance of integrating genetic and functional data in studies of primary cancer samples."Authors Klco JM,Spencer DH,Miller CA,Griffith M,Lamprecht TL,O'Laughlin M,Fronick C,Magrini V,Demeter RT,Fulton RS,Eades WC,Link DC,Graubert TA,Walter MJ,Mardis ER,Dipersio JF,Wilson RK,Ley TJ5.Journal of immunology (Baltimore, Md. : 1950)Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis.2013"45-9459 was used in Flow cytometry/Cell sorting to investigate how blocking the HLA-DR2b allele with small molecule inhibitors may offer a promising therapeutic strategy for the treatment of multiple sclerosis."Authors Ji N,Somanaboeina A,Dixit A,Kawamura K,Hayward NJ,Self C,Olson GL,Forsthuber TG

技术参数

产品应用 Flow

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://biorod.cn/thread-16694.htm
产品询价需求提交
最新回复 (0)
返回
发布信息
扫码添加客服微信,咨询产品报价