ANTI-HU CD105 (ENDOGLIN)(SN6) APC

2024-10-17

ANTI-HU CD105 (ENDOGLIN)(SN6) APC

货号:17-1057-41,17-1057-42

规格:25T,100T

价格:1442,3163

产品类型:流式抗体

品牌:eBioscience

抗原:CD105

物种:人

宿主:小鼠

抗体亚型:IgG

克隆号:SN6

荧光染料:APC

抗体类型:单抗同型对照:IgG1, kappa
免疫原性:用法:5uL(0.25 µg)/test(Flow)
Description: The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin. CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.Applications Reported: The SN6 antibody has been reported for use in flow cytometric analysis.Applications Tested: This SN6 antibody has been pre-titrated and tested by flow cytometric analysis of U937 cell line. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2 µm post-manufacturing filtered.
数据

CD105 (Endoglin) Antibody (17-1057-41) in FlowStaining of U937 cells with Mouse IgG1 K Isotype Control APC (Product # 17-4714-81) (blue histogram) or Anti-Human CD105 (Endoglin) APC (purple histogram). Total viable cells were used for analysis.
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参考文献:
1.Cell researchSIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.2016"17-1057 was used in Flow cytometry/Cell sorting to investigate whether human SIRT6 has a direct role in maintaining the homeostasis of mesodermal tissues, showing that it safeguards against oxidative stress by coactivating NRF2."Authors Pan H,Guan D,Liu X,Li J,Wang L,Wu J,Zhou J,Zhang W,Ren R,Zhang W,Li Y,Yang J,Hao Y,Yuan T,Yuan G,Wang H,Ju Z,Mao Z,Li J,Qu J,Tang F,Liu GH2.BiomaterialsMesenchymal stromal cells form vascular tubes when placed in fibrin sealant and accelerate wound healing in vivo.2015"17-1057 was used in Flow cytometry/Cell sorting to show that ADSCs are able to form tubular structures within fibrin gels, and may also contribute to faster wound healing."Authors Mendez JJ,Ghaedi M,Sivarapatna A,Dimitrievska S,Shao Z,Osuji CO,Steinbacher DM,Leffell DJ,Niklason LE3.Stem cells and cloning : advances and applicationsHuman adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction.2015"17-1057 was used in Flow cytometry/Cell sorting to investigate the potential use of adipose-derived stem cells."Authors Davy PM,Lye KD,Mathews J,Owens JB,Chow AY,Wong L,Moisyadi S,Allsopp RC4.EMBO molecular medicineEmbelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing.2014"17-1057 was used in Flow cytometry/Cell sorting to demonstrate a novel therapy to control pathological neoangiogenesis while sparing normal vasculature."Authors Coutelle O,Hornig-Do HT,Witt A,Andree M,Schiffmann LM,Piekarek M,Brinkmann K,Seeger JM,Liwschitz M,Miwa S,Hallek M,Krönke M,Trifunovic A,Eming SA,Wiesner RJ,Hacker UT,Kashkar H5.OncotargetFOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells.2014"17-1057 was used in Flow cytometry/Cell sorting to study the effect of fusion of mesenchymal stem cells with lung cancer cells, showing that fusion is mediated by FOXF1 and leads to a more benign state due to complementation of tumorigenic defects such as the restoration of p21 function."Authors Wei HJ,Nickoloff JA,Chen WH,Liu HY,Lo WC,Chang YT,Yang PC,Wu CW,Williams DF,Gelovani JG,Deng WP

技术参数

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