| 1.BloodIdentifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations."45-0458 was used in Flow cytometry/Cell sorting to develop assays capable of distinguishing a variety of defects in the CTLA-4 pathway."Authors Hou TZ,Verma N,Wanders J,Kennedy A,Soskic B,Janman D,Halliday N,Rowshanravan B,Worth A,Qasim W,Baxendale H,Stauss H,Seneviratne S,Neth O,Olbrich P,Hambleton S,Arkwright PD,Burns SO,Walker LS,Sansom DM2.HaematologicaA distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia."45-0458 was used in Flow cytometry/Cell sorting to characterise the B- and T- cell compartments in patients with primary immune thrombocytopenia."Authors Flint SM,Gibson A,Lucas G,Nandigam R,Taylor L,Provan D,Newland AC,Savage CO,Henderson RB3.PLoS neglected tropical diseasesHyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells."45-0458 was used in Flow cytometry/Cell sorting to provide initial evidence that elevated frequencies of Th17 and Th2 cells form part of the immune network instigating the development of severe onchocerciasis."Authors Katawa G,Layland LE,Debrah AY,von Horn C,Batsa L,Kwarteng A,Arriens S,W Taylor D,Specht S,Hoerauf A,Adjobimey T4.PLoS pathogensChronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis."45-0458 was used in Flow cytometry/Cell sorting to define the mechanisms behind immune cell maintenance in HIV infected individuals."Authors Le Saout C,Hasley RB,Imamichi H,Tcheung L,Hu Z,Luckey MA,Park JH,Durum SK,Smith M,Rupert AW,Sneller MC,Lane HC,Catalfamo M5.Journal of immunology (Baltimore, Md. : 1950)Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells."45-0458 was used in Flow cytometry/Cell sorting to investigate novel strategies to generate in vitro-induced Tregs."Authors Mota C,Nunes-Silva V,Pires AR,Matoso P,Victorino RM,Sousa AE,Caramalho I |
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