Anti-Human CD3 SAFIRE Purified
货号:05121-20
规格:100μg
价格:4130
产品类型:流式抗体
品牌:Biogems
物种:其它
宿主:其它
抗体亚型:其它
克隆号:OKT3
荧光染料:其它
抗体类型: | | 同型对照: | Mouse IgG2a, kappa |
免疫原性: | | 用法: | |
The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
参考文献: |
Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New YorkKnapp W(1989)Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3.Human Antibodies,5(1), 41-47. |