Mitofilin Monoclonal Antibody (MM#7A-2E4AD5), Alexa Fluor 647

货号：MA4-56400-A647

规格：50 µl

价格：4070

产品类型：流式抗体

品牌：Thermo Fisher

物种：人/小鼠/大鼠

宿主：小鼠

抗体亚型：其它

荧光染料：Alexa Fluor 647

类型:	单抗	同型对照：	IgG1
免疫原性：	Human heart mitochondria	用法：	1-10 µg/mL(IF);1-10 µg/mL(ICC)

Target InformationMitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

数据

Mitofilin Antibody (MA4-56400-A647) in IFImmunofluorescent analysis of Mitofilin (red) in HeLa cells. The cells were fixed with 4% Paraformaldehyde in PBS for 15 minutes at room temperature, and blocked with 3% BSA in PBS (Product # 37525) for 30 minutes at room temperature. Cells were stained with a Mitofilin Monoclonal Antibody, AlexaFluor 647 conjugate (Product # MA4-56400-A647) at a dilution of 2.5 µg/mL in blocking buffer for 1 hour at room temperature protected from light. Nuclei (blue) were stained with Hoechst Dye (Product # 62249) at a dilution of 1:10,000 in blocking buffer. Images were taken on a Thermo Scientific ToxInsight Instrument at 20X magnification.

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