OCT4 Polyclonal Antibody, DyLight 488
货号:PA5-22735
规格:100 µL
价格:5548
产品类型:流式抗体
品牌:Thermo Fisher
物种:人/小鼠/大鼠
宿主:兔
抗体亚型:IgG
荧光染料:DyLight 488
类型: | 多抗 | 同型对照: | IgG |
免疫原性: | A synthetic peptide made to an internal portion of the human OCT4 protein sequence (between residues 100-200). | 用法: | 2µg/mL(WB) |
Product Specific InformationThe target sequence has 93% sequence homology with bovine and porcine.Target InformationStem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC) had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another. The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.