SOX2 Polyclonal Antibody

货号：PA5-85143

规格：100 µL

价格：4806

产品类型：流式抗体

品牌：Thermo Fisher

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：Alexa Fluor plus 680

类型:	多抗	同型对照：	IgG
免疫原性：	Recombinant protein encompassing a sequence within the center region of human SOX2.	用法：	1:50-1:200（Flow);1:100-1:1000(ICC);1:100-1:1000(IF);1:500-1:3000(WB)

Product Specific InformationKeep as concentrated solution.Positive Control: NT2D1, A431, Human ESC, GL261.Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Target InformationSOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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