PDX1 Polyclonal Antibody

货号：PA5-87695

规格：100 µL

价格：4732

产品类型：免疫组化一抗

品牌：eBioscience

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：Purified

类型:	多抗	同型对照：
浓度：	2.27 mg/mL	用法：	1：500-1：1000 (WB)
免疫原性：	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDX

产品详细信息Immunogen sequence: MNGEEQYYAA TQLYKDPCAF LLAVHAAVRP LGAGPDAEAQ LRRLQLSADP ERPGRFRLEL LGAGPGAVNL EWPLESVSYT IRGPTQHELQ PPPGGPGTLS LHFLNPQEAQ RWAVLVRGAT VEGQNGSKSN SPPALGPEAC PVSLPSPPEA STLKGPPPEA DLPRSPGNLT; Positive Samples: DU145, HepG2, Mouse pancreas, Mouse liver; Cellular Location: Cytoplasm, Nucleus, cytosol靶标信息PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in its gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

数据

PDX1 Antibody (PA5-87695) in WB Western blot analysis of extracts of various cell lines, using PDX1 Polyclonal antibody (Product # PA5-87695) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 90s.

二抗荧光二抗免疫组化一抗标签抗体

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技术参数

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