PDX1 Polyclonal Antibody
货号：PA5-69028
规格：100 µL
价格：6049
产品类型：免疫组化一抗
品牌：eBioscience
物种：人/小鼠/大鼠
宿主：兔
抗体亚型：IgG
荧光染料：Purified
类型: | 多抗 | 同型对照： | |
浓度： | | 用法： | 1.0 µg/mL(WB) |
免疫原性： | synthetic peptide directed towards the middle region of rat PDX1 |
产品详细信息This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%靶标信息pdx-1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription.Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.
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