Phospho-PDX1 (Ser66) Polyclonal Antibody
货号： PA5-64702
规格：100 µL
价格：5956
产品类型：免疫组化一抗
品牌：eBioscience
物种：人/小鼠/大鼠
宿主：兔
抗体亚型：IgG
荧光染料：Purified
类型: | 多抗 | 同型对照： | |
浓度： | 1 mg/mL | 用法： | 1：1000 (WB) |
免疫原性： | A synthesized peptide derived from human PDX1 (Phospho-Ser66) |
产品详细信息
Phospho-PDX1 (Ser66) Polyclonal Antibody detects endogenous levels of PDX1 only when phosphorylated at Ser66.
靶标信息
pdx-1 (pancreas duodenum homeobox-1, also known as IPF-1, IDX-1, and STF-1) is a transcription factor that has been shown to activate insulin, glucokinase, IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. Additionally, pdx-1 has been studied for its role in pancreatic development which includes maturation and differentiation of pancreatic precursor cells. Mutations in the pdx-1 gene have been shown to cause pancreatic agenesis, maturity-onset diabetes of the young, and type II diabetes.
数据 |
| Phospho-PDX1 (Ser66) Antibody (PA5-64702) in WB Western blot analysis of PDX1 in EGF treated A431 whole cell lysates using a Phospho-PDX1 (Ser66) Polyclonal Antibody (Product # PA5-64702). |
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| 二抗荧光二抗免疫组化一抗标签抗体 |
| 参考文献： |
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