N-CAM1 Human ELISA Kit/人N-CAM1 ELISA试剂盒
货号：EHNCAM1,EHNCAM1X5,EHNCAM1X10
规格：96 tests,5X96 tests,10X96 tests
价格：7238,29826,52892
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.5 ng/mL |
| 检测范围 | 0.61-150 ng/mL |
样本类型/体积 | 上清液 100 μL 血清 10 μL 血浆 10 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 分析稀释浓缩液 - 生物素化检测抗体 -SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD56 (NCAM) |
| Protein aliases | antigen recognized by monoclonal antibody 5.1H11, CD56, N-CAM-1, NCAM-1, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CD56, MSK39, NCAM, NCAM1 |
| Gene ID | (Human) 4684 |
| Gene symbol | NCAM1 |
| UniProt ID | (Human) P13591 |
| The Human Neuronal Cell Adhesion Molecule-1(Hu N-CAM1) ELISA quantitates Hu N-CAM1 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu N-CAM1.人神经元细胞粘附分子1（人N-CAM1）ELISA定量分析人血清，血浆或细胞培养基中的人N-CAM1。 该检测试剂盒将专门识别天然和重组人N-CAM1。Principle of the method 方法原理The Human N-CAM1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人N-CAM1固相夹心ELISA（酶联免疫吸附测定）设计用于测量匹配的抗体对之间结合的靶标量。 已在提供的微孔板的孔中预包被了靶标特异性抗体。 然后将样品，标准液或质控品添加到这些孔中，并与固定的（捕获）抗体结合。 通过添加第二（检测）抗体形成三明治，添加底物溶液，该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。 该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试，其标准包括敏感性，特异性，精密度和批次间一致性。 有关验证的更多信息，请参见手册。Target information 靶标信息CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.CD56（NCAM，神经细胞粘附分子）是一种免疫球蛋白家族的跨膜糖蛋白，可作为粘附分子，在神经系统中以120-180 kDa的同工型广泛表达。 CD56存在于T细胞和NK细胞上，并参与细胞迁移，轴突生长，寻路和突触可塑性。 多唾液酸修饰导致CD56介导的细胞粘附减少。 CD56通过其细胞外区域，通过结合细胞外基质成分（如层粘连蛋白和整联蛋白）介导同型和异型相互作用。 CD56在大多数神经外胚层衍生的细胞系，组织和肿瘤（例如视网膜母细胞瘤，髓母细胞瘤，星形细胞瘤和神经母细胞瘤）中表达。 此外，CD56是广泛使用的神经内分泌标记物，对神经内分泌肿瘤和卵巢颗粒细胞肿瘤具有高敏感性。 与CD56功能障碍相关的疾病包括狂犬病和弹状浆细胞样树突状细胞瘤。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-20418.htm
QQ:1749072012