S6 (Phospho) [pS240/pS244] Human InstantOne ELISA Kit/人S6 (Phospho) [pS240/pS244] InstantOne ELISA试剂盒
货号：85-86194-11
规格：96 tests
价格：0
产品类型：InstantOne ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
样本类型/体积 | 细胞裂解液 20μL |
操作时间 | 1 hr 20 min |
测试时间 | 1 hr 10 min |
Homogenous (no wash) | No |
仪器设备 | Colorimetric microplate reader 酶标仪 |
规格 | 96 Tests |
组份 | - 捕获抗体 - 检测抗体 - InstantOne 检测板 - 细胞裂解液 - 增强剂溶液 - 洗涤液（10X） - 底物试剂（TMB） - 终止液 - 阳性对照细胞裂解物（冻干） - 密封条 |
储存温度 | 2-8℃ |
| Protein name | S6 |
物种（Tested） | 人 |
试剂盒类型 | InstantOne ELISA |
检测抗体偶联物 | Biotin |
标记（染料） | HRP |
| Gene ID | (Human) 6194 |
| Gene symbol | RPS6 |
Gene aliases | S6 |
UniProt ID | (Human) P62753 |
| The InstantOne™ ELISA is specifically engineered for accurate measurement of phosphorylated human S6 ribosomal protein (RP) (Ser240/244) in cell lysates. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate.InstantOne™ELISA是专门设计用于准确测量细胞裂解物中磷酸化的人S6核糖体蛋白（RP）（Ser240 / 244）的。 InstantOne™ELISA试剂盒可在大约一小时内快速分析样品。 将传统的夹心ELISA中使用的所有试剂均以溶液形式添加到板上，然后进行洗涤步骤，并使用TMB比色底物进行检测。Target information 靶标信息Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.核糖体是催化蛋白质合成的细胞器，由一个小的40S亚基和一个大的60S亚基组成。 这些亚基一起由4种RNA种类和大约80种结构不同的蛋白质组成。 该基因编码胞质核糖体蛋白，该蛋白是40S亚基的一个组成部分。 该蛋白质属于核糖体蛋白S6E家族。 它是核糖体中蛋白激酶的主要底物，具有5个C端丝氨酸残基的子集，被不同的蛋白激酶磷酸化。 磷酸化由多种刺激物诱导，包括生长因子，肿瘤促进剂和促分裂原。 去磷酸化发生在生长停滞期。 该蛋白可能通过选择性翻译特定类别的mRNA来帮助控制细胞的生长和增殖。 正如编码核糖体蛋白的基因的典型特征一样，该基因有多个经过处理的假基因分散在基因组中。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用，不用于诊断过程，未经明确授权不得转售。 |
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