CD15 Monoclonal Antibody (HI98), FITC, eBioscience™

货号：11-0159-41,11-0159-42

规格：25 tests,100 tests

价格：822,1855

产品类型：流式抗体

品牌：eBioscience

抗原：CD15

物种：人

宿主：小鼠

抗体亚型：IgG

克隆号：HI98

荧光染料：FITC

抗体类型:	流式抗体	同型对照：	Mouse IgM Isotype Control (11E10), FITC, eBioscience™
浓度：	5 µL/Test	用法：	5 μL(0.125 μg)/test (Flow)

产品详细信息Description: The HI98 monoclonal antibody reacts with human CD15, Lewis X. This 3-fucosyl-N-acetyllactosamine carbohydrate moiety is expressed by granulocytes. Monocytes express this structure at varying degree while lymphocytes are negative.Applications Reported: The HI98 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HI98 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered. 靶标信息CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

数据

CD15 Antibody (11-0159-41) in Flow Staining of normal human peripheral blood cells with Mouse IgM Isotype Control FITC (Product # 11-4752-80) (blue histogram) or Anti-Human CD15 FITC (purple histogram). Cells in the granulocyte gate were used for analysis. CD15 Antibody (11-0159-41)The Journal of clinical investigation 2016 -Published figure using CD15 monoclonal antibody (Product # 11-0159-41)

推荐产品：

▪ 流抗抗体

参考文献：

1. Stem cells (Dayton, Ohio) Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells.2. Cancer cell Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.3. PloS one A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model.4. Oncotarget Stimulation of medulloblastoma stem cells differentiation by a peptidomimetic targeting neuropilin-1.5. The Journal of clinical investigation Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia.

技术参数

产品应用 Flow;WB;IF;IHC

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://biorod.cn/thread-22289.htm