SARS-CoV-2 Nucleocapsid Antibody (001)/抗体
货号：NBP2-90988-100ul
规格：100ul
价格：6181
产品类型：抗体和ELISA
品牌：NOVUS
| 抗体类型: | 单抗 | 同型对照： | IgG |
| 免疫原性： | Fischer rat immunized with 4-8 cell stage mouse embryos | 用法： | 1:1000 - 1:5000（WB）；1:5000 - 1:10000（ELISA） |
Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). Seven coronaviruses had been found to cause human infection including SARS-CoV-2/2019-nCoV resulting in a potentially fatal atypical pneumonia, named COVID-19. SARS-CoV-2 has 4 major structural proteins including spike (S), envelope (E), membrane (M), and nucleocapsid (N), which share significant sequence homology with SARS-CoV. The most prominent protein in the culture supernatants infected with SARS virus is the 46 kDa nucleocapsid protein. SARS-CoV-2 nucleocapsid protein is critical for packaging the viral genome via protein oligomerization. Additionally, the SARS-CoV nucleocapsid protein has been implicated in other functions such as the modulation of host cellular processes including cell cycle deregulation, inhibition of IFN production, and induction of proinflammatory factors (e.g. COX-2).
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