Human CMASP-3 ELISA Kit/人CMASP-3 ELISA试剂盒
货号:EH113RB,EH113RBX5,EH113RBX10
规格:96 tests,5X96 tests,10X96 tests
价格:6641,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:人
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.6 ng/mL |
检测范围 | 150-0.6 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | MASP1 |
Protein aliases | C4/C2 activating component of Ra-reactive factor, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor), Mannan-binding lectin serine protease 1, Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Mannose-binding lectin-associated serine protease 1, Mannose-binding protein-associated serine protease, MASP-1, Ra-reactive factor serine protease p100, RaRF, Serine protease 5 |
物种(Tested) | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | 3MC1, CRARF, CRARF1, MAP1, MAp44, MASP, MASP1, MASP3, PRSS5, RaRF |
Gene ID | (Human) 5648 |
Gene symbol | MASP1 |
UniProt ID | (Human) P48740 |
Human CMASP-3 quantitates human CMASP-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CMASP-3.人CMASP-3定量检测血清,血浆,上清液中的人CMASP-3。 该检测试剂盒将专门识别天然和重组人CMASP-3。Target information 靶标信息MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.MBL是免疫反应中的关键组成部分,因为它可以通过Ab独立机制直接触发入侵微生物的中和。 人MBL的突变与免疫缺陷有关,该免疫缺陷是由于突变的MBL启动补体固定的能力降低而引起的。 在人类中,三种类型的与MBL相关的丝氨酸蛋白酶MASP-1,MASP-2和MASP-3,以及截短形式的MASP-2(小的与MBL相关的蛋白; sMAP或MAp19)与MBL结合以激活凝集素 补体系统的途径。 MASP-3是MASP-1基因的另一种剪接产物。 MASP-1和MASP-3之间的重链/ A链相同,但轻链/ B链完全不同。 活化的MASP随后裂解并活化补体途径的下游组分。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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