Human Legumain ELISA Kit/人Legumain ELISA试剂盒
货号：EH299RB,EH299RBX5,EH299RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 28.7 pg/mL |
| 检测范围 | 28.7-7,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | LGMN |
| Protein aliases | Asparaginyl endopeptidase, cysteine protease 1, Legumain, Protease, cysteine 1, protease, cysteine, 1 (legumain) |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | AEP, LGMN, LGMN1, PRSC1 |
| Gene ID | (Human) 5641 |
| Gene symbol | LGMN |
| UniProt ID | (Human) Q99538 |
| Human Legumain quantitates human Legumain in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Legumain.人Legumain定量检测血清，血浆，上清液中的人Legumain。 该检测试剂盒将专门识别天然和重组人Legumain。Target information 靶标信息This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.该基因编码对天冬酰胺基键的水解具有严格特异性的半胱氨酸蛋白酶。 该酶可能参与溶酶体/内体系统中II类MHC呈递的细菌肽和内源蛋白的加工。 酶的活化是由酸性pH触发的，并且似乎是自催化的。 蛋白表达在单核细胞分化为树突状细胞后发生。 脂多糖在成熟的树突状细胞中表达后会产生完全成熟的活性酶。 该基因的过表达可能与大多数实体瘤类型有关。 该基因在13号染色体上有一个假基因。已经描述了几种选择性剪接的转录变体，但仅确定了两个的生物学有效性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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