Human MMP-12 ELISA Kit/人MMP-12 ELISA试剂盒
货号：EH327RB,EH327RBX5,EH327RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.04 ng/mL |
| 检测范围 | 0.04-10 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | MMP12 |
| Protein aliases | Macrophage elastase, Macrophage metalloelastase, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12 (macrophage elastase), Matrix metalloproteinase-12, ME, MME, MMP-12 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | HME, ME, MME, MMP-12, MMP12 |
| Gene ID | (Human) 4321 |
| Gene symbol | MMP12 |
| UniProt ID | (Human) P39900 |
| Human MMP-12 quantitates human MMP-12 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human MMP-12.人MMP-12可定量检测血清，血浆，上清液中的人MMP-12。 该检测试剂盒将专门识别天然和重组人MMP-12。Target information 靶标信息Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.基质金属蛋白酶（MMP）家族的蛋白质在正常生理过程（例如胚胎发育，繁殖和组织重塑）以及疾病过程（例如关节炎和转移）中参与细胞外基质的分解。 大多数MMP被分泌为无活性的前蛋白，当被细胞外蛋白酶切割时被激活。 据认为，由该基因编码的蛋白质在两端均被切割以产生活性酶，但是该过程尚未被充分描述。 该酶降解可溶和不可溶的弹性蛋白。 它可能在动脉瘤的形成中起作用，对小鼠的研究表明在肺气肿的形成中也有作用。 该基因是定位于染色体11q22.3的MMP基因簇的一部分。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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