Human OX40L ELISA Kit/人OX40L ELISA试剂盒
货号：EH356RB,EH356RBX5,EH356RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 61 pg/mL |
| 检测范围 | 61-15,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | OX40L (CD252) |
| Protein aliases | CD134 ligand, CD252, Glycoprotein Gp34, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, tax-transcriptionally activated glycoprotein 1 (34kD), tumor necrosis factor (ligand) superfamily member 4, tumor necrosis factor ligand 2B, Tumor necrosis factor ligand superfamily member 4 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CD134L, CD252, GP34, OX-40L, OX4OL, TNFSF4, TNLG2B, TXGP1 |
| Gene ID | (Human) 7292 |
| Gene symbol | TNFSF4 |
| UniProt ID | (Human) P23510 |
| Human OX40L quantitates human OX40L in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human OX40L.人OX40L定量测定血清，血浆，上清液中的人OX40L。 该检测试剂盒将专门识别天然和重组人OX40L。Target information 靶标信息The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.肿瘤坏死因子超家族成员TNFSF4是II型膜结合的非共价连接的同源三聚体蛋白。 它在抗原呈递细胞（例如树突状细胞和活化的B细胞）上表达，并在其他细胞（例如血管内皮细胞，肥大细胞和自然杀伤细胞）上表达。 TNFSF4信号特别通过TNFRSF4受体表达，主要在CD4 + T细胞上表达，但在某些活化的CD8 + T细胞上也表达。 TNFRSF4 / TNFSF4起到共刺激信号的作用，这是抗原呈递细胞与其靶T细胞之间产生有效相互作用所必需的。 它增强细胞增殖和存活，并增加RANTES，IL-2，IL-3和IFNγ的表达。 TNFRSF4 / TNFSF4信号传导在免疫耐受中起重要作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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