Human PCSK2 ELISA Kit/人PCSK2 ELISA试剂盒
货号：EH363RB,EH363RBX5,EH363RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 2.45 ng/mL |
| 检测范围 | 2.458-600 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | PCSK2 |
| Protein aliases | KEX2-like endoprotease 2, NEC 2, Neuroendocrine convertase 2, PC2, Prohormone convertase 2, Proprotein convertase 2 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | NEC 2, NEC-2, NEC2, PC2, PCSK2, SPC2 |
| Gene ID | (Human) 5126 |
| Gene symbol | PCSK2 |
| UniProt ID | (Human) P16519 |
| Human PCSK2 quantitates human PCSK2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PCSK2.人PCSK2定量检测血清，血浆，上清液中的人PCSK2。 该检测试剂盒将专门识别天然和重组人PCSK2。Target information 靶标信息The subtilisin-like prohormone convertase (PC) family is a group of cellular enzymes that cleave most prohormones and neuropeptide precursors. Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous approximately 10 kDa amino-terminal proregion, a highly conserved approximately 55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.枯草杆菌蛋白酶样激素原转化酶（PC）家族是一类裂解大多数激素和神经肽前体的细胞酶。通过组成型分泌途径转运的许多其他细胞蛋白，一些病毒蛋白和细菌毒素也被PC靶向成熟。 PC家族成员具有相似的结构，包括异质的约10 kDa氨基末端前区，高度保守的约55 kDa枯草杆菌蛋白酶样催化结构域和长度和序列异质的羧基端结构域。这些酶在适当的细胞区室中前区切割后变得具有催化活性。 PC家庭成员的亚细胞定位各不相同。免疫定位研究表明，PC1可以在核周区域以及反高尔基体网络中找到，而PC2可以在反高尔基体网络中以及分散地分布在周围细胞质中。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。 |
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