RNF40 Polyclonal Antibody

货号：PA5-92980

规格：100 µL

价格：4732

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant fusion protein containing a sequence c

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	3.14 mg/mL	用法：	1:50-1:200(ChIP);1:20-1:100(ICC)；1:20-1:100 (IF);1:500-1:2000(WB)

产品详细信息Immunogen sequence: MSGPGNKRAA GDGGSGPPEK KLSREEKTTT TLIEPIRLGG ISSTEEMDLK VLQFKNKKLA ERLEQRQACE DELRERIEKL EKRQATDDAT LLIVNRYWAQ LDETVEALLR CHESQGELSS APEAPGTQEG PTCDGTPLPE PGTSELRDPL LMQLRPPLSE PALAFVVALG ASSSEEVELE LQGRMEFSKA AVSRVVEASD RLQRRVEELC QRVYSRGDSE PLSEAAQAHT RELGRENRRL QDLATQLQEK HHRISLEYSE LQDKVTSAET KVLEMETTVE DLQWDIEKLR KREQKLNKHL; Positive Samples: MCF7, HepG2, U-937; Cellular Location: Nucleus 靶标信息The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

数据：

RNF40 Antibody (PA5-92980) in ICCImmunocytochemistry-Immunofluorescence analysis of RNF40 was performed in U2OS cells using RNF40 Polyclonal Antibody (Product # PA5-92980). RNF40 Antibody (PA5-92980) in WBWestern Blot analysis of RNF40 in extracts of various cell lines using RNF40 Polyclonal Antibody (Product # PA5-92980) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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