| Description: This AD2 monoclonal antibody reacts with human CD73, a 5'-ectonucleotidase that converts 5'-adenosine monophosphate to adenosine. CD73 is expressed on the surface of endothelial cells, as well as B and T cells, including some CD4+Foxp3+ regulatory T cells. Adenosine production by these cells has been linked to the inhibition of CD4 T cell effector functions such as proliferation and cytokine secretion.Applications Reported: This AD2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This AD2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2 µm post-manufacturing filtered. |
| 1.Stem cell research and therapyHuman umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.2017"12-0739 was used in Flow cytometry/Cell sorting to investigate the potential of hUCMSCs in improving ovarian function and withstanding ovarian senescence."Authors Li J,Mao Q,He J,She H,Zhang Z,Yin C2.BiomaterialsMesenchymal stromal cells form vascular tubes when placed in fibrin sealant and accelerate wound healing in vivo.2015"12-0739 was used in Flow cytometry/Cell sorting to show that ADSCs are able to form tubular structures within fibrin gels, and may also contribute to faster wound healing."Authors Mendez JJ,Ghaedi M,Sivarapatna A,Dimitrievska S,Shao Z,Osuji CO,Steinbacher DM,Leffell DJ,Niklason LE |
QQ:1749072012