Human Alpha 2-M ELISA Kit/人Alpha 2-M ELISA试剂盒
货号：EH20RB,EH20RBX5,EH20RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 4 ng/mL |
| 检测范围 | 4-3,000 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | A2M |
| Protein aliases | Alpha-2-M, Alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | A2M, A2MD, CPAMD5, FWP007, S863-7 |
| Gene ID | (Human) 2 |
| Gene symbol | A2M |
| UniProt ID | (Human) P01023 |
| Human Alpha 2-M quantitates human Alpha 2-M in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Alpha 2-M.人Alpha 2-M定量检测血清，血浆，上清液中的Alpha 2-M。 该检测试剂盒将专门识别天然和重组人Alpha 2-M。Target information 靶标信息Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.α2-巨球蛋白（a2M）是大约720 kDa的同四聚体糖蛋白，由四个相同的大约180 kDa的亚基组成。 aAlpha 2M与其他α-巨球蛋白（例如补体成分C3和C4和妊娠区蛋白PZP）共享，对多种配体具有非凡的结合能力。 这允许α-巨球蛋白充当针对血浆中外源肽的体液防御屏障。 Alpha 2M相互作用并捕获几乎任何蛋白酶，通常称为泛蛋白酶抑制剂。 在阿尔茨海默氏病（AD）患者的大脑中，Alpha 2M也已经被定位为弥散性淀粉样斑块，支持了alpha 2M在AD病因学中的重要作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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