Human IL-17 RB ELISA Kit/人IL-17 RB ELISA试剂盒
货号：EH261RB,EH261RBX5,EH261RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6327,28472,54564
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.85 ng/mL |
| 检测范围 | 0.85-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL17RB |
| Protein aliases | cytokine receptor CRL4, Cytokine receptor-like 4, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, interleukin 17 receptor homolog 1, interleukin 17B receptor, Interleukin-17 receptor B, Interleukin-17B receptor |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CRL4, EVI27, IL17BR, IL17RB, IL17RH1, UNQ2501/PRO19612 |
| Gene ID | (Human) 55540 |
| Gene symbol | IL17RB |
| UniProt ID | (Human) Q9NRM6 |
| Human IL-17 RB quantitates human IL-17 RB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-17 RB.人IL-17 RB定量测定血清，血浆，上清液中的人IL-17 RB。该检测试剂盒将只识别天然和重组人IL-17 RB。Target information 靶标信息Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.最近，已经鉴定出许多属于白介素（IL）-17家族的细胞因子。这些被称为IL-17B，IL-17C（1）和IL-17E。 IL-17是一种有效的促炎细胞因子，可在多种疾病中发挥作用，包括类风湿性关节炎，多发性硬化和促进肿瘤生长。 IL-17B，C和E像IL-17一样能够诱导促炎反应。但是，它们不与IL-17受体结合，表明可能存在其他与IL-17R相关的受体。 IL-17B和IL-17E的受体已独立分离，分别命名为EV127（小鼠）和IL-17Rh1（人类）。 IL-17E诱导NF-kB途径的激活，并且像IL-17一样也诱导IL-8的产生。 IL-17Rh1 mRNA在肾脏和肝脏中高表达，在小肠，结肠和脑中呈中等水平。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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