Human Transglutaminase 2/TGM2 ELISA Kit/人转谷氨酰胺酶2 / TGM2 ELISA试剂盒
货号:EH462RB,EH462RBX5,EH462RBX10
规格:96 tests,5X96 tests,10X96 tests
价格:6641,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:人
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.82 ng/mL |
检测范围 | 0.82-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | TGM2 |
Protein aliases | C polypeptide, protein-glutamine-gamma-glutamyltransferase, Protein-glutamine gamma-glutamyltransferase 2, TG(C), TGase C, TGase H, TGase-2, Tissue transglutaminase, Transglutaminase C, Transglutaminase H, Transglutaminase-2 |
物种(Tested) | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | TG(C), TGC, TGM2 |
Gene ID | (Human) 7052 |
Gene symbol | TGM2 |
UniProt ID | (Human) P21980 |
Human Transglutaminase 2/TGM2 quantitates human Transglutaminase 2/TGM2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Transglutaminase 2/TGM2.人转谷氨酰胺酶2 / TGM2定量检测血清,血浆,上清液中的人转谷氨酰胺酶2 / TGM2。 该检测试剂盒将专门识别天然和重组人转谷氨酰胺酶2 / TGM2。Target information 靶标信息Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity. In mammals, eight distinct TGase isoenzymes have been identified. Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains. tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis. In the Alzheimer's disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.转谷氨酰胺酶(TGase)通过形成e-(g-谷氨酰基)赖氨酸异肽键来催化蛋白质的交联,并且需要Ca2 +的结合才能发挥其活性。 在哺乳动物中,已鉴定出八种不同的TGase同工酶。 组织转谷氨酰胺酶(tTGase),也称为TGase 2,具有四个不同的域:N端b三明治,催化核心和两个C端b桶结构域。 tTGase可能在细胞死亡,细胞增殖,细胞分化和受体介导的内吞作用中起作用。 在阿尔茨海默氏病脑中,tTGase活性升高是由许多蛋白(包括Ab肽,b淀粉样前体蛋白和tau蛋白)聚合并形成神经原纤维缠结而表现出来的。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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