ING3 Polyclonal Antibody

货号：PA5-102988

规格：100 µL

价格：4711

产品类型：标签抗体

品牌：Thermo Fisher

抗原：A synthesized peptide derived from human ING3, cor

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1mg/mL	用法：	1:200（IHC）；1:1000-1:3000(WB)

靶标信息The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

数据：

ING3 Antibody (PA5-102988) in IHC (P)Immunohistochemistry analysis of paraffin-embedded ING3 in mouse muscle tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with ING3 polyclonal antibody (Product # PA5-102988) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit. ING3 Antibody (PA5-102988) in WBWestern blot analysis of ING3 in HeLa cell lysate. Samples were incubated with ING3 polyclonal antibody (Product # PA5-102988).

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技术参数

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