Human Cathepsin C ELISA Kit/人组织蛋白酶C ELISA试剂盒
货号：EH73RB,EH73RBX5,EH73RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 2 ng/mL |
| 检测范围 | 2-500 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Cathepsin C |
| Protein aliases | Cathepsin C, Cathepsin J, Dipeptidyl peptidase 1, Dipeptidyl peptidase 1 exclusion domain chain, Dipeptidyl peptidase 1 heavy chain, Dipeptidyl peptidase 1 light chain, Dipeptidyl peptidase I, Dipeptidyl peptidase I exclusion domain chain, Dipeptidyl peptidase I heavy chain, Dipeptidyl peptidase I light chain, Dipeptidyl transferase, dipeptidyl-peptidase I, DPP-I |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CPPI, CTSC, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS |
| Gene ID | (Human) 1075 |
| Gene symbol | CTSC |
| UniProt ID | (Human) P53634 |
| Human Cathepsin C quantitates human Cathepsin C in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cathepsin C.人组织蛋白酶C可定量测定血清，血浆，上清液中的人组织蛋白酶C。该检测试剂盒将专门识别天然和重组人组织蛋白酶C。Target information 靶标信息Cathepsin C, known also as dipeptidyl aminopeptidase I (DPPI), is a tetrameric lysosomal cysteine peptidase belonging to the papain family. Cathepsin C is involved in intracellular protein degradation and the processing of protein precursors, where it participates in cell growth, neuraminidase activation, and platelet factor XIII activation. Cathepsin C is largely related to other lysosomal cysteine proteinases, including cathepsin B, H and L. Enzymatically, Cathepsin C is capable of sequentially removing dipeptides from the amino terminus, and it requires halide ions, namely chloride ions, and thiols for complete enzymatic activity. Protein levels of Cathepsin C are detected in a variety of tissues, and it is most highly expressed in spleen, kidney, cytotoxic lymphocytes and myeloid cells, where it localizes to the secretory granule compartment. Cathepsin C is initially synthesized as a proenzyme that is rapidly processed to generate two distinct chains that function together as the mature form of the enzyme.组织蛋白酶C，也称为二肽基氨基肽酶I（DPPI），是属于木瓜蛋白酶家族的四聚体溶酶体半胱氨酸肽酶。组织蛋白酶C参与细胞内蛋白质降解和蛋白质前体的加工，在其中参与细胞生长，神经氨酸酶活化和血小板因子XIII活化。组织蛋白酶C在很大程度上与其他溶酶体半胱氨酸蛋白酶有关，包括组织蛋白酶B，H和L。在酶学上，组织蛋白酶C能够从氨基末端顺序去除二肽，并且它需要卤离子（即氯离子）和硫醇才能完全发挥酶的作用。 。在多种组织中都检测到组织蛋白酶C的蛋白质水平，并且在脾脏，肾脏，细胞毒性淋巴细胞和髓样细胞中高度表达，并定位在分泌性颗粒腔室中。组织蛋白酶C最初是作为一种原酶进行合成的，可以快速加工以生成两条不同的链，这些链一起作为酶的成熟形式发挥作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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