Human Glypican 3 ELISA Kit/人Glypican 3 ELISA试剂盒
货号：EH223RB,EH223RBX5,EH223RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.8 ng/mL |
| 检测范围 | 0.8-600 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Glypican 3 |
| Protein aliases | glypican proteoglycan 3, Glypican-3, Glypican-3 alpha subunit, Glypican-3 beta subunit, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, secreted glypican-3 |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | DGSX, GPC3, GTR2-2, MXR7, OCI-5, OCI5, SDYS, SGB, SGBS, SGBS1 |
| Gene ID | (Human) 2719 |
| Gene symbol | GPC3 |
| UniProt ID | (Human) P51654 |
| Human Glypican 3 quantitates human Glypican 3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Glypican 3.人Glypican 3定量测定血清，血浆，上清液中的人Glypican 3。该检测试剂盒将专门识别天然和重组人Glypican 3。Target information 靶标信息GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.GPC3是带有硫酸乙酰肝素的细胞表面蛋白聚糖。该蛋白质可能参与主要在中胚层组织和器官中的生长的抑制/调节，并且可能在调节IGF2与其受体的相互作用中起作用，从而调节其功能。 Glypican相关的整体膜蛋白聚糖家族的成员包含通过糖基磷脂酰肌醇（GPI）连接锚定到细胞质膜的核心蛋白。这些蛋白质可能在控制细胞分裂，生长调节和肿瘤易感性中起作用。 GPC3中的缺失突变是Simpson-Golabi-Behmel综合征（SGBS）的原因，也称为Simpson畸形综合征（SDYS）。 SGBS是一种以内脏和骨骼异常为特征的产前和产后过度生长（巨人症）的疾病。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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